113 results
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... of active pulmonary ... decreased reflexes Pathophysiology ... of bacilli to bone ... for concomitant pulmonary
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... Infertility • Decr Bone ... fractures • Short ... sleep apnea, cor pulmonale ... Syndrome #genetics #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Osteoarthritis (OA): Clinical ... in subchondral bone ... contact between bony ... Osteoarthritis #OA #pathophysiology ... diagnosis #signs #symptoms
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Trauma to the long bone ... Pathophysiology ... onset widespread pulmonary ... FES is a clinical ... Diagnosis #Signs #Symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in GBA1 gene Clinical ... Osteonecrosis, bone ... Diagnosis #Signs #Symptoms
Yergason's Test on Physical Exam
Yergason's test for biceps tendon pathology testing stability of the tendon within
flexion elicits symptoms ... - Lil Bone Peep ... #PhysicalExam #clinical ... #video #msk #sports
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... lipolysis Signs/Symptoms ... deficiency: - Short ... endocrinology #pathophysiology
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
Pathogenesis and Clinical ... insertion into bone ... , ridging, oil spots ... PsoriaticArthritis #pathophysiology ... diagnosis #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... 3: Necrosis of bone ... destroying thin bony ... #Mastoiditis #pathophysiology ... #signs #symptoms