20 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Most common symptoms ... symptoms - Pain ... - Drugs - Primary
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Algorithm Tumours ... - See Bone Lesions ... Pelvis - Positive Alkaline ... Phosphate Deficiency Primary ... #Algorithm #Orthopedics
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... - Differential Diagnosis ... Algorithm Metastatic ... #Differential #Diagnosis ... #Algorithm #Orthopedics
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Difficulty walking Diagnosis ... • Elevation of urinary
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis ... Secondary #Tertiary #pathophysiology
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
- Differential Diagnosis ... Algorithm Exostotic ... Constitutional Symptoms ... #Differential #Diagnosis ... #Algorithm #Orthopedics
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Somatoform Disorders - Differential Diagnosis Algorithm
 - Patient presents with complex medical problem or symptoms that
- Differential Diagnosis ... Algorithm - Patient ... Motivation is primary ... Somatoform Disorder - One ... #Algorithm #Psychiatry
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
- Differential Diagnosis ... Algorithm Primary ... Cytokine-Mediated Bone ... Milk Alkali) • ... #Differential #Diagnosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT, Alkaline ... CAST) • ALT: primarily ... Other locations: bone ... Bilirubin #Hepatology #Pathophysiology ... #Diagnosis #LFTs