17 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... Differential Diagnosis Algorithm ... Most common symptoms ... symptoms - Pain ... Differential #Diagnosis #Algorithm
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Differential Diagnosis Algorithm ... Constitutional Symptoms ... #Mass #Tumor #BoneLesion ... Differential #Diagnosis #Algorithm ... #Orthopedics #Causes
Amyloidosis - Workup and Diagnostic Algorithm
 • Serum Immunofixation and Serum Free Light Chains
 • Biopsy
and Diagnostic Algorithm ... skin, fat pad, bone ... chain ratio • Bone ... amyloid (i .e. mass ... • CBC, CMP, alkaline
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Hypophosphatasia Is Low Alkaline ... collection with EDTA Pathophysiology ... mineralization Symptoms ... of Low Alkaline
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Differential Diagnosis Algorithm ... Tumours - See Bone ... Pelvis - Positive Alkaline ... Gastrointestinal Disease • Bone ... #Orthopedics #Causes
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... mass) • Post-menopausal ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT, Alkaline ... mitochondria (mAST ... within liver Alkaline ... Other locations: bone ... Bilirubin #Hepatology #Pathophysiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in one ... Retinoblastoma Signs / Symptoms ... inflammation • Spheroid mass ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... lateral hip Signs/Symptoms ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics