28 results
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
commonly fractured carpal ... bone. ... "pooping duck sign ... bone fracture ... "pooping duck sign
Ossification of Carpal Bones

It’s always tricky to remember the age of ossification of the carpal bones
Ossification of Carpal ... ossification of the carpal ... interpreting a Pediatric ... -6-7 years for Triquetral ... Diagnosis #Peds #Pediatrics
Age of Ossification of Carpal Bones
Capitate - 1 Month
Hamate - 2 Months
Triquetral - 3 Years
Lunate -
Ossification of Carpal ... Bones Capitate ... Hamate - 2 Months Triquetral ... bones! ... diagnosis #msk #pediatrics
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
different types of bone ... involucrum • Paget disease ... phase • Paget disease ... blade of grass sign ... Radiology #XRay #MSK #pediatrics
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Gauchers #Disease ... #Diagnosis #Signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... activates lipolysis Signs ... expansion (e.g. carpal ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... Cardiovascular disease ... Overproduction #diagnosis #signs ... endocrinology #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... Infertility • Decr Bone ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... of bacilli to bone