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diagnosis hematology management oncology algorithm syndrome aplastic mds myelodysplastic platelets rheumatology workup abscess alkaline alp arteritis ascorbicacid cirrhosis classification dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... effect following treatment ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... #Differential # ... #hematology #secondary
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... Diagnosis #causes ... #Platelets #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... hyperplasia of bone ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... Platelet Count - Differential ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Platelets #Differential
Causes of Aplastic Anemia #Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... #Anemia #Causes ... #Pathophysiology ... #Pathology #Treatment ... #Management #Differential
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... • Bone marrow ... only curative treatment ... #hematology #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... changes), high MCV anemia ... candidate) - Bone ... Platelet #Disorders #Differential ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... and petechiae Causes ... • Suggested by bone ... Treatment: ... #oncology #hematology
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