29 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... hyperplasia of bone ... Hemolysis #Hemolytic #Anemia ... #Differential #Causes ... #Workup #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... with hypocellular bone ... #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... • Bone marrow ... #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
practices that could cause ... changes), high MCV anemia ... candidate) - Bone ... or if a primary hematologic ... #Workup #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... and petechiae Causes ... • Suggested by bone ... #oncology #hematology ... #diagnosis #management
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... produced in the bone ... Pancytopenia is a hematologic ... These causes could
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Causes of Hyperferritinemia ... be used by the bone ... Most Common Causes ... Hematologic Malignancy ... Sideroblastic anemia
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... Drug induced - Bone ... - Hemolytic anemia ... Differential #Diagnosis #hematology ... #rheumatology #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • softening of bones ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology