17 results
diagnosis treatment hemophagocytic lymphohistiocytosis clinical oncology rheumatology syndrome blood infection product reactions skin acne activation anemia aplastic atopic atopy cellulitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... /ml, ↑ LDH • Bone ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... / Diagnosis: HLH ... Hemophagocytosis in bone ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... CD163 staining of bone ... is found in the bone ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... • Bone marrow ... acute leukemia Management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Treatment Primary HLH ... steroids • In mild cases ... Options for severe cases ... #Treatment #management ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... months temperate zones ... 10% Crab, few cases ... rash #cellulitis #dermatology ... legs #clinical #photo
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... anymore • Routine bone ... classification #hematology ... #oncology #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... and petechiae Causes ... • Suggested by bone ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... Hemophagocytosis in bone ... Approach • Initial management ... #Hematology #HemeOnc
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