71 results
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment ... Algorithm for MAS / HLH ... Lymphohistiocytosis #Management ... #Treatment #Algorithm ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... /ml, ↑ LDH • Bone ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Causes of Hyperferritinemia ... be used by the bone ... HLH or Adult Onset ... Hematologic Malignancy ... In adults, HLH is
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... Hemophagocytosis in bone ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... • Bone marrow ... only curative treatment ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... autoimmune disease, treatment ... Options for severe cases ... #Treatment #management ... #hematology
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... by an ↑ rate of bone ... • Caused by ( ... #diagnosis #management ... #treatment
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... out additional causes ... including liver and hematologic ... If other causes ... algorithm #diagnosis #management
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
with hypocellular bone ... megaloblastic anemia Treatment ... Anemia #diagnosis #management ... #treatment #hematology