114 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... and less common diseases ... polychondritis • Behcet disease ... #inflammatory #differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... - Highest • Bone ... Most common symptoms ... - Bone symptoms ... ALP #Elevation #Differential
Vertebral Body Abnormalities

A sheet of common (and uncommon) vertebral body findings, because a completely “normal” spine
Vertebra Hurler Syndrome ... Morquio Syndrome ... Hemivertebra Scheuermann Disease ... Sclerotic Mets Bone ... #differential
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
, Kidney Disease ... - Accelerated Bone ... Formation: Hungy Bone ... Syndrome - ... endocrinology #differential
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup and Differential ... HLH syndrome 5. ... marrow failure syndrome ... Metastatic Disease ... Pancytopenia #Workup #Differential
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... Infertility • Decr Bone ... #genetics #pathophysiology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
paresthetica • Symptoms ... 3-6 months of symptom ... intervertebral disc disease ... MeralgiaParesthetica #MSK #pathophysiology ... #differential #
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... (SLE) Signs / Symptoms ... #Pathophysiology ... Diagnosis #Signs #Symptoms