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differential management hematology msk signs pathophysiology workup orthopedics syndrome treatment clinical neurology oncology rheumatology anemia endocrinology hepatology cardiology radiology summary
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
of Bone • Characterized ... by an ↑ rate of bone ... and formation of bone ... • Caused by ( ... #Bone #diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Bone Lesion on X-Ray - Differential Diagnosis Algorithm Exostotic • Osteochondroma Asymptomatic &/or Non-Active Bone Scam •
Bone Lesion on X-Ray ... /or Non-Active Bone ... • Unicameral Bone ... Constitutional Symptoms ... #Causes
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm True Vertigo - Illusion of Rotary Movement Peripheral Vestibular
Causes of Dizziness ... Algorithm True ... • Meniere's Disease ... Media • Temporal Bone ... #Algorithm #Causes
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
- Differential Diagnosis ... Algorithm Elevated ... Granulomatous Disease ... Miscellaneous - Bone ... #Algorithm #causes
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... BrighamChiefs #Bone ... #differential #diagnosis
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... pathophysiology #signs #symptoms ... #diagnosis
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
- Differential Diagnosis ... Algorithm Tumours ... - See Bone Lesions ... • Bone Marrow ... #Causes
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... Most cases diagnosed ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
Primary Bone Tumors ... - Differential Diagnosis ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Causes #Oncology
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