17 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... aplasia • ITP ... Warm AIHA • Bone ... #oncology #hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Increased red cell ... hyperplasia of bone ... Increased red cell ... Differential #Causes #Workup ... #Hematology #Diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... with hypocellular bone ... Consider stem cell ... Medicine @SCVMCMed #Aplastic ... management #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... = Hypocellular bone ... Anemia Clinical ... #hematology #diagnosis
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
an old house & works ... differential: basal cell ... ca, squamous cell ... #SkinRash #dermatology ... #clinical #photo
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... • Bone marrow ... Allogeneic stem cell ... Management #treatment #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
No evidence of anemia ... marrow plasma cells ... insufficiency, Anemia ... to the plasma cell ... #Significance #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Hypoproliferative (i.e. bone ... Hypogonadism • Bone ... marrow failure: Aplastic ... defects (e.g. sickle cell ... Production #Index #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... more: • Clonal bone ... marrow plasma cell ... , B and T cell lymphoproliferative ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... low red blood cell ... • Aplastic Anemia ... Workup: • Complete ... Syndromes #diagnosis #hematology