18 results
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
in elderly Causes ... damage weakens the bone ... #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Intra-articulation fracture ... - Aneurysmal bone ... #msk #physicalexam
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... in US Features ... • Bone marrow ... #Management #treatment ... #hematology #oncology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Greater Trochanter Fracture ... Valgus position of knee ... #causes #symptoms ... #signs #diagnosis ... #msk
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... formation MSK ... -> Pathologic fractures ... PagetsDisease #pathophysiology ... #diagnosis #signs
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Treatment: • ... #summary #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
pain Clinical Features ... • A clinical diagnosis ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... worrisome EKG features ... Syndrome #TLS #diagnosis ... #management #hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... Mucous membranes • Bone ... nonimmune hemolysis MSK ... , or any other cause ... vasculitis Treatment
Transient Patellar Dislocation - MSK Radiology
Imaging Findings:
 • Hyperintense marrow edema of the anterolateral femoral condyle
Dislocation - MSK ... consistent with bone ... There is also a bone ... injury of the knee ... #msk