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diagnosis management hematology hepatology differential neurology signs treatment alkaline phosphatase workup abnormal agammaglobulinemia als amyotrophic anemia anorexianervosa barre bells biliary
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... - Highest • Bone ... Most common symptoms ... symptoms - Pain ... Differential #Diagnosis #Algorithm
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... collection with EDTA Pathophysiology ... mineralization Symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
and Management Summary ... decreased reflexes Pathophysiology ... of bacilli to bone ... should be done in ALL ... Diagnosis #Management #Summary
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
and Management Summary ... Symptoms of metastatic ... Bone scan is indicated ... patients with bone ... pain and ↑ ALP
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... suspicious clinical symptoms ... box indicates all ... ALP, alkaline phosphatase ... LFTs #Abnormal #Algorithm
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management Summary ... Hypercellular bone ... When present, symptoms ... • Treatment algorithms ... Diagnosis #Management #Summary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) - Summary ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... Nucleotidase • ALT ... obstruction • ALP
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... Get an LP and imaging ... Returning Traveler’ algorithm ... Bone marrow biopsy
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphocyte predominant (LP ... pattern of spread, B symptoms ... Classification #pathophysiology ... #differential #algorithm
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Griscelli, Purtilo (XLP ... management #treatment #summary
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