86 results
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... the first-line treatments ... which reduces bone ... #Pharmacology #Pathophysiology
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
the articular bone ... Peri-articular osteopenia (bones ... Diagnosis #Radiology #Clinical ... #Pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • softening of bones ... of feet, thigh bones ... Neuropathy ALP is critical ... collection with EDTA Pathophysiology
Alzheimer's Disease - Summary
 • Epidemiology
 • Pathophysiology
 • Risk Factors
 • Presentation
 • Diagnosis
 •
Epidemiology • Pathophysiology ... Diagnosis • Treatment ... • Clinical Course
Pulmonary Embolism Therapies

Aligning therapeutic options with the severity of pulmonary embolism. Yellow boxes represent therapies requiring
Yellow boxes represent ... in prospective clinical ... Severity #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... , Biological + Bone ... Assessment • Clinical ... /ml, ↑ LDH • Bone
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in GBA1 gene Clinical ... Osteonecrosis, bone
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... Rheumatic pain Clinical ... • Bone and joint ... Diagnosis: • A clinical ... and lower jaw Treatment
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Pathogenesis, clinical ... and underlying bone ... joint capsule or bone ... #orthopedics #pathophysiology