49 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... damage weakens the bone ... Femur #Fractures #msk ... #differential #causes ... #pathophysiology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Bone marrow ... only curative treatment ... Myelodysplastic #Syndrome
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... Trauma to the long bone ... accounts for —9096 of cases ... Pathophysiology ... Fat #Embolism #Syndrome
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... Rule out other causes ... and lower jaw Treatment ... #SAPHO #Syndrome
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework Bone ... /Joint Causes of ... Patellofemoral pain syndrome ... Hematoma Venous Causes ... lower #extremity #msk
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
fractured long bone ... Marfan's Syndrome ... • Dislocated Bone ... Vascular #JointPain #MSK ... #Orthopedics #Causes
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... organ damage • Treatment ... : • Pathophysiology ... Low calcium • Treatment
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... changes and may cause ... hyperparathyroidism Treatment ... are the leading cause ... Differential #Diagnosis #Pathophysiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment