25 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... IBD • Chronic liver ... #Osteoporosis #pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... ALT: • AST: liver ... In liver, 80% of ... Other locations: bone ... Bilirubin #Hepatology #Pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... , bone, placenta ... • softening of bones ... of feet, thigh bones ... collection with EDTA Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone: • Liver ... Incr IGF1 • Bone ... endocrinology #pathophysiology
Pneumoperitoneum from perforated duodenal ulcer on RUQ POCUS

Male with severe RUQ abdominal pain. Answer in thread.
duodenal ulcer on RUQ POCUS ... anterior to the liver ... Robert Jones @RJonesSonoEM ... duodenal #ulcer #RUQ #POCUS
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
Vitamin D
processes in the liver ... and stimulating bone ... #Pathophysiology
Mirizzi Syndrome on RUQ POCUS

Adult male-RUQ abd pain.VSS/Afeb. WBC-16.8K. Obstructive pattern on hepatic panel with normal
Syndrome on RUQ POCUS ... Robert Jones @RJonesSonoEM ... Mirizzi #Syndrome #Liver ... #POCUS #Ultrasound
Multiple Hepatic Metastases on Liver POCUS
Another case of Stage 4 Colon CA patient with sepsis. Multiple
Metastases on Liver ... POCUS Another ... Robert Jones @RJonesSonoEM ... Hepatic #Metastases #Liver ... #POCUS #ultrasound
Side Effects of the Neobladder - Pathophysiology
 • Hercalciuria → Kidney Stones
 • Bone Resorption →
the Neobladder - Pathophysiology ... Kidney Stones • Bone ... Increased burden on liver ... #SideEffects #Pathophysiology
Hepatic Metastases on POCUS 
Patient with history of colon cancer presents with right flank pain. Focused
Metastases on POCUS ... have multiple liver ... Robert Jones @RJonesSonoEM ... Hepatic #Metastases #Liver ... #POCUS #clinical