131 results
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Phosphate Physical Symptoms ... signs, Fragile bones ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Secondary #Tertiary #pathophysiology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... the first-line treatments ... which reduces bone ... #Pharmacology #Pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... resorption in the bone ... resorption in the bone ... Hypercalcemia #Malignancy #Pathophysiology ... #Differential #
MonkeyPox Virus - Summary Review - What we know so far

 • History
 • Epidemiology
 •
• Signs and Symptoms ... Transmission • Differential ... Diagnosis • Treatment ... #microbiology #treatment
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... - Highest • Bone ... Most common symptoms ... symptoms - Pain ... ALP #Elevation #Differential
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
paresthetica • Symptoms ... 3-6 months of symptom ... mass Sensory Symptoms ... MeralgiaParesthetica #MSK #pathophysiology ... #differential #
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... Highlighted boxes ... indicate preferred treatment ... perceived level of symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... Diagnosis #Signs #Symptoms