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diagnosis treatment oncology thrombocytopenia vasculitis adultonset allergy anemia aplastic apml causes checklist cirrhosis classification coagulation common cvid dic differentiation disease
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV, HIV ... splenomegaly • Hepatic ... #treatment #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis and Management ... skin necrosis (at injection ... Management: • ... re-challenge >100d after Dx ... #Treatment #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
helmet cells DDX ... deficiency) • HIT ... 100mg/dL) - Heparin ... causes #treatment #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... and thymoma DDX ... Anemia #oncology #hematology ... #diagnosis #management
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... Framework The DDx ... NSAIDs/Aspirin, IV ... • Parasitic infections ... #Diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
initiation • Differential ... Diagnosis: Infection ... • Steroids: IV ... APML #diagnosis #management ... #hematology #oncology
VIBES Mnemonic - Cirrhosis Management Checklist V - Volume (Ascites, HRS) - Evaluate for Ascites, Edema, Hydrothorax, Hepatorenal
Mnemonic - Cirrhosis Management ... paracentesis / TIPS I - Infection ... (Variceal) - Ddx ... beta-blockers E - Hepatic ... #Diagnosis #Hepatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... to exclude are infections ... CTD) • ANCA (Dx ... Cryoglobulins • HIV ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... to exclude are infections ... drug exposure or Dx ... #Diagnosis #Rheumatology
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