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diagnosis pathophysiology wrist msk peds radiology age endocrinology feedbackloop fracture genetics gh growthhormone management mnemonic orthopedics pagetsdisease pituitary praderwilli signs
Ossification of Carpal Bones It’s always tricky to remember the age of ossification of the carpal bones
Carpal Bones ... of the carpal bones ... interpreting a Pediatric ... -6-7 years for Triquetral ... #Carpal #Bones
Age of Ossification of Carpal Bones Capitate - 1 Month Hamate - 2 Months Triquetral - 3 Years Lunate -
of Carpal Bones ... Hamate - 2 Months Triquetral ... of the carpal bones ... #Age #Carpal #Bones ... diagnosis #msk #pediatrics
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
commonly fractured carpal ... bone. ... bone fracture ... • Complications ... #Wrist #Carpal
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... chondrocytes -> Incr ossification ... lipolysis Signs/Symptoms ... expansion (e.g. carpal
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... /Complications: ... Infertility • Decr Bone ... pathophysiology #peds #pediatrics
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... cause excessive bone ... the vertebral canal ... diagnosis #signs #symptoms ... #complications
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