31 results
Ossification of Carpal Bones

It’s always tricky to remember the age of ossification of the carpal bones
Ossification of ... remember the age of ossification ... and sequence of ossification ... -6-7 years for Triquetral ... drdevradiology #Ossification
Age of Ossification of Carpal Bones
Capitate - 1 Month
Hamate - 2 Months
Triquetral - 3 Years
Lunate -
Age of Ossification ... of Carpal Bones ... Hamate - 2 Months Triquetral ... of the carpal bones ... #Age #Carpal #Bones
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
Symptoms of Hypophosphatemia ... Hallucinations, Fatigue • Hematologic ... Heart failure • Bones ... Growth retardation, Bone ... Hypophosphatemia #Phosphate #Symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... chondrocytes -> Incr ossification ... lipolysis Signs/Symptoms
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Most common symptoms ... symptoms - Pain ... Diagnosis #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... mineralization Symptoms ... Hyophosphatasia #hepatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... with hypocellular bone ... management #treatment #hematology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
fragmentation and mild bone ... possible secondary ossification ... tear (similar symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... #Leukemia #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
pylori test (GI symptoms ... candidate) - Bone ... or if a primary hematologic ... Causes #Workup #hematology