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diagnosis endocrinology signs pathophysiology bones growthhormone pediatrics wrist acromegaly age arthritis clinical dermatology differential ear earpain excess features feedbackloop herpeszoster
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... chondrocytes -> Incr ossification ... lipolysis Signs/Symptoms ... abn lipid • GH ... expansion (e.g. carpal
Age of Ossification of Carpal Bones Capitate - 1 Month Hamate - 2 Months Triquetral - 3 Years Lunate -
Age of Ossification ... of Carpal Bones ... Hamate - 2 Months Triquetral ... of the carpal bones ... #Age #Carpal #Bones
Ossification of Carpal Bones It’s always tricky to remember the age of ossification of the carpal bones
Ossification of ... Carpal Bones ... of the carpal bones ... -6-7 years for Triquetral ... #Carpal #Bones
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... overgrowth: • Carpal ... Tunnel Syndrome ... diagnosis #signs #symptoms
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... decade → peripheral/acral ... • GH stimulates ... Beckwith Wiedemann syndrome ... (Lanreotide) ± GH
Ramsay Hunt Syndrome - Herpes Zoster Oticus Triad: 1. Ipsilateral facial paralysis 2. Ear pain 3. Vesicles
Ramsay Hunt Syndrome ... in the auditory canal ... Guillain-Barré syndrome ... • Stroke syndromes ... Oticus #Diagnosis #Symptoms
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Involvement, Spares DIP, Carpal ... Tunnel, Sicca Syndrome ... Instability, Felty's Syndrome ... rheumatology #signs #symptoms
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... peripheries, Carpal ... timel syndrome, ... Features #Signs #Symptoms
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... dermatosis (Sweets Syndrome ... Episcleritis Signs and Symptoms ... development of skin symptoms ... Erythema nodosum - Acral
Strongyloides Stercoralis on sputum microscopy As many suggested this was strongyloides stercoralis hyperinfection syndrome. Infection is initiated by
hyperinfection syndrome ... asymptomatic or minimal symptoms ... Hyperinfection syndrome ... exacerbation of GI/pulm symptoms ... there is increased larval
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