55 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
: Proximal tubule ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... in the distal tubule ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... hypokalemia • Renal tubular ... , Gitelman's syndrome ... #nephrology #potassium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Defects in Kidney Tubule ... ascending limb Gitelman ... distal convoluted tubule ... Liddle syndrome ... Defects #Kidney #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
SAME, Cushing Syndrome ... diuretics, Bartter syndrome ... , Gitelman syndrom ... Diagnosis #Algorithm #causes ... potassium #low #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... blood flow • Tubular ... damage • Tubular ... #Mechanisms #pathophysiology ... #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Diagnosis Renal Causes ... Familial: Bartter syndrome ... and Gitelman syndrome ... hypomagnesemia Renal Causes ... #nephrology #magnesium
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Transient renal tubular ... - Gitelman ... syndrome - ... - Hungry bones syndrome ... Classification #Causes
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
anions • Renal tubular ... acidosis • Gitelman's ... syndrome • Bartter's ... syndrome Extrarenal ... Diagnosis #Algorithm #Causes
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology