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diagnosis management symptoms causes hematology neurology vasculitis night physicalexam sweats acromegaly adies algorithm apml arterial arteritis arthritis autoimmune behcet blurry
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... • Pathophysiology ... diagnosis #management #hematology
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Ehlers-Danlos syndrome ... • Down, Turner ... , Marfan syndromes ... #Keratoconus #pathophysiology ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Important Causes of Diplopia TIER 1-CRITICAL Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn TIER 2-EMERGENT: Vertebral dissection, Myasthenia gravis,
, Orbital apex syndrome ... URGENT: Brainstem tumor ... Miller-Fisher syndrome ... mass #Diplopia #differential ... #diagnosis #ophthalmology
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm Relative Afferent Pupil Defect • Optic Neuritis • Ischemic
Pupillary Defects - Differential ... Midbrain (Parinaud's Syndrome ... ): • Tumor • ... Pupils #Defects #Differential ... Algorithm #Causes #Ophthalmology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behcet disease) Differential ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs ... #symptoms #rheumatology
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Holmes-Adie Syndrome ... Young females Differential ... trauma/orbital tumor ... PhysicalExam #neurology #ophthalmology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Tumor-associated ... Lymphadenopathy • Tumor-associated ... #joint #pain #differential ... #diagnosis #rheumatology
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... • Tumor-induced ... • Nephrotic syndrome ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... • Acute stroke syndromes ... system: Brain tumor ... Lack of UMN/LMN signs ... #Weakness #Differential
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