13 results
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ICU transfer • Tumor ... #Tumor #Lysis # ... Syndrome #diagnosis ... #management #oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... Laboratory TLS ... #diagnosis #management ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... high WBC count cause ... /- rasburicase Tumor ... of tumor cells ... #TLS #diagnosis
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
Mechanisms - Tumor ... lysis syndrome ... #Differential #Diagnosis ... Magnesium #Table #Causes ... #Management
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... wandering_er #Tumor ... #Lysis #Syndrome ... #TLS #oncology ... #management #UricAcid
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... EMERGENCIES: Tumor ... Lysis Syndrome: ... Constipation • Nausea ... #differential #diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... low Ca - q8 h TLS ... Treat underlying cause ... #HemeOnc #Diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
diuretics, Saline infusion ... Acidosis, Cell Lysis ... (TLS, rhabdo/crush ... acidosis), CK+LDH (lysis ... only if no clear cause
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... : laparoscopic tumor ... reserved for large or invasive ... tumors. ... (chemotherapy, tumor
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Classification: • The tumor ... predominant HL - The tumor ... lymph node biopsy (diagnostic ... classification #hematology #oncology ... #management