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diagnosis differential hepatology management rheumatology alkaline alp candida candidemia coagulation demyelinating dic dili diseases disseminated druginduced endocrinology erythematosus fever fungemia
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... Rickets Dysmorphic Features ... Deprivation • Primary ... Anorexia Nervosa • CNS ... endocrinology #causes
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thromboembolism (7%) • CNS ... Treatment: • Treat primary ... cause • Correct ... Coagulation #diagnosis #causes ... treatment #management #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... DILI suspicion Features ... for alternative causes ... biliary obstruction, Primary ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• recurrent fractures ... membrane into the CNS ... pain - Frequent fractures ... Phosphatase: • Other causes ... • Elevation of urinary
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... jirovecii • CNS ... or Neutrophil Dysfunction ... #Causes #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... ducts Clinical Features ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... the context of primary ... syndrome Clinical Features ... and CNS • Headache ... mild cognitive dysfunction
Invasive Fungal Infection (IFI) Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
with neutropenia, hematologic ... (most frequent cause ... Aspergillus species (primarily ... species (commonly CNS ... include fever, organ dysfunction
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM What Are Demyelinating Diseases? • Conditions that damage myelin, the protective
nervous system (CNS ... Progressive (SPMS) - Primary ... autoimmune/infectious causes ... bladder/bowel dysfunction ... diseases #neurology #CNS
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