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diagnosis hematology differential causes bruising laboratory teg abnormal aptt blanching bruise chemistry dic disorders disseminated ecchymosis hematomas hemostasis hepatology inr
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
(INR), Normal PTT ... PT (INR) - Bleeding ... PT (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... Tests - Prolonged PT ... and Prolonged PT ... #Coagulation #Abnormal
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... • Prolonged PT ... Fibrinogen: ↓ • PT ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... ) ABNORMAL PT ... PT/ABNORMAL PTT
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... #Bleeding #Bruising ... Differential #Diagnosis #Algorithm
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
are typical of coagulation ... Type O blood normally ... levels tend to be normal ... , PT should be normal ... Measurement of coagulation
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
Normal Thromboelastogram ... Diagnosis #Hematology #Coagulation ... #Thromboelastogram ... #TEG #Normal #Interpretation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Chemistries - Interpretation ... - If both are normal ... • Albumin • Coagulation ... factors: PT/INR ... RBC (hemolysis, bleeding
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... routine transfusion algorithms ... Thromboelastography #Thromboelastogram ... #TEG #interpretation
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