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diagnosis management rheumatology algorithm hepatology oncology workup causes knee radiology alkaline anemia biliary cirrhosis complications hodgkins lesions lymphoma neurology pagetsdisease
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... stimulation (placenta/Bone ... - Highest • Bone ... - Bone symptoms ... - Drugs - Primary
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Diagram of different types of bone tumors that can occur around the knee on XRay -
Diagram of different types ... of bone tumors ... ) • Enostosis/bone ... docskalski #Knee #Bone ... Tumors #Diagnosis #Bony
Diagram of different types of bone tumors that can occur around the knee on XRay Age <
Diagram of different types ... of bone tumors ... blade of grass sign ... #Differential # ... Radiology #XRay #MSK
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Tumours - See Bone ... Phosphate Deficiency Primary ... • Bone Marrow ... Malignancy • Drugs (e.g ... Fractures #Pathologic #MSK
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... Elevated ALP 2.
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Pathophsiology ... Neurological involvement (type ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types ... on: - Cell type ... involvement Differential ... CML, ALL) • Solid ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... : Inhibitor of bone ... formation causing poor bone ... mineralization Symptoms ... Skeletal: - Bone
Paget’s Disease: Pathogenesis and Clinical Findings • Incr serum CTx - marker of bone resorption •
Paget’s Disease: ... CTx - marker of bone ... resorption • Lytic bone ... - marker of bone ... #symptoms
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