36 results
Diagram of different types of bone tumors that can occur around the knee on XRay -
Diagram of different types ... of bone tumors ... ) • Enostosis/bone ... docskalski #Knee #Bone ... Tumors #Diagnosis #Bony
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
Diagram of different types ... of bone tumors ... blade of grass sign ... #Differential # ... Radiology #XRay #MSK
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Tumours - See Bone ... Phosphate Deficiency Primary ... • Bone Marrow ... Malignancy • Drugs (e.g ... Fractures #Pathologic #MSK
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Pathophsiology ... Neurological involvement (type ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young adults ... translocation • Types ... on: - Cell type ... involvement Differential ... oncology #diagnosis #differential
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... Deprivation • Primary ... • Cushing's Disease ... Panhypopituitarism Treatment ... Chemotherapy • Bone
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... presents in young adults ... Presentation - Young adults ... Signs and symptoms ... • Primary Progressive
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... : Inhibitor of bone ... formation causing poor bone ... mineralization Symptoms ... Skeletal: - Bone
Paget’s Disease: Pathogenesis and Clinical Findings

 • Incr serum CTx - marker of bone resorption
 •
Paget’s Disease: ... CTx - marker of bone ... resorption • Lytic bone ... ALP - marker of bone ... #symptoms