54 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Diagram of different types of bone tumors that can occur around the knee on XRay -
Diagram of different types ... of bone tumors ... ) • Enostosis/bone ... docskalski #Knee #Bone ... Tumors #Diagnosis #Bony
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... stimulation (placenta/Bone ... - Highest • Bone ... - Bone symptoms ... - Drugs - Primary
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
Diagram of different types ... of bone tumors ... blade of grass sign ... #Differential # ... Radiology #XRay #MSK
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Tumours - See Bone ... Phosphate Deficiency Primary ... • Bone Marrow ... Malignancy • Drugs (e.g ... Fractures #Pathologic #MSK
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Pathophsiology ... Neurological involvement (type ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... • Myopathy (Also ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
translocation • Types ... on: - Cell type ... , but can also arise ... involvement Differential ... oncology #diagnosis #differential
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
There is also fragmentation ... and mild bone marrow ... tibial tuberosity Differential ... tear (similar symptoms ... marrow edema and bony
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... Deprivation • Primary ... • Cushing's Disease ... Panhypopituitarism Treatment ... Chemotherapy • Bone