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nephrology acute causes glomerulonephritis lupus rpgn sle vasculitis aki algorithm casts classification druginduced erythematosus failure glomerular hematuria injury kidneyinjury management
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
of Glomerular Diseases ... #differential # ... spectrum #diagnosis ... #nephrology #nephritic ... #nephrotic #comparison
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and Disease ... broad - Advanced kidney ... disease Red blood ... Urinary #Casts #Differential ... #Microscopy #Diagnosis
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Interstitial nephritis ... • Inflammatory disease ... /phimosis #Diagnosis ... Postrenal #Failure #Differential ... #Nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
causes of Acute Kidney ... Injury AKI - Differential ... Diagnosis HEMODYNAMIC ... Acute Interstitial Nephritis ... #Diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus Nephritis ... • Limited to Kidney ... involvement: Anti-GBM Disease ... #diagnosis #algorithm ... #rheumatology
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Diagnosis Renal ... - Interstitial nephritis ... Medullary sponge kidney ... necrosis, Sickle cell disease ... #urology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
) - Loss of kidney ... of glomerular disease ... nephropathy, lupus nephritis ... Classification #Differential ... #Diagnosis #Nephrology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... ulcers, Lupus nephritis ... Evolution: Chronic disease ... #table #rheumatology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... affects the skin, neurologic ... musculoskeletal systems • Kidneys ... #Diagnosis #Rheumatology
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