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Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria (RBC casts ... #Nephritic #Nephrotic ... #Syndrome #Comparison ... #Diagnosis
Acute Kidney Injury (AKI) - Common Patterns on Urinalysis
 - Prerenal
 - ATN
 - AIN
 -
Acute Kidney Injury ... - Nephrotic Syndrome ... - Nephritic Syndrome ... #Urinalysis #diagnosis ... #table #comparison
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Syndrome and Nephritic ... Red blood cell casts ... Red blood cell casts ... #Comparison #Table ... #Nephrology #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... RBC casts in urine ... severe cases ... may be in nephrotic ... #Diagnosis
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... • Glomerular: Nephrotic ... , Nephritic • ... Interstitium (AIN ... drtonydang @CMC_IM #AKI
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Interstitial Nephritis ... sterile pyuria, WBC casts ... proteinuria, granular casts ... #Interstitial #Nephritis ... #nephrology #diagnosis
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... heme-granular casts ... are seen in acute ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... in creatinine by ... Epithelial cell casts ... Interstitial Nephritis ... #Causes
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Simplified Approach to Acute ... Urinary obstruction, Nephrotoxic ... cases are caused ... for WBCs, RBCs, casts ... #Acute #KidneyInjury
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of acute ... a variety of acute ... suggestive of nephrotic ... Urine #Microscopy #nephrology ... interpretation #diagnosis