21 results
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
Christmas Tree Rash ... parallel to lines of skin ... palms/soles - Differential ... diagnosis: secondary ... #photo #PhysicalExam
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... normal - Hemolysis, NASH ... #Injury #hepatology ... transaminitis #differential ... #diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... or symptoms of liver ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis ... #management #pathophysiology
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Lives in an old ... Diagnosis? ... heaped up borders); differential ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... deficiency • Liver ... #Diagnosis #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #management #treatment ... #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... disease: > 2 • NASH ... #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Criteria for Diagnosis ... Skin involvement ... Resolution > 15 days Differentials ... #diagnosis #management