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differential dermatology oncology erythematosus sle systemic causes treatment vasculitis algorithm anemia classification hemeonc intravascular joint leukemia pain product rash reactions
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... the peripheral blood ... hemolytic uremic syndrome ... , Hematology 2012 ... , p 193 #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... signs #symptoms #diagnosis ... #rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
nose chondritis, skin ... vasculitis • Hematologic ... macrocytic anemia, thrombocytopenia ... including peripheral blood ... Autoinflammatory #Somatic #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #SLE #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... thrombosis and/or blood-brain ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... leukopenia, anemia, and thrombocytopenia ... #Diagnosis #Management ... #Hematology #Rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
and Management ... arterial thrombosis, skin ... exposure (prevent skin ... #Diagnosis #Management ... #Treatment #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... usually IgG) (e.g. lupus ... #hematology #anemia
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