26 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis ... , causes and management ... manifestations - Skin ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... Vasculitis 1 ... Hyperviscosity syndrome ... #Vasculitis #Diagnosis ... #Rheumatology #
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
vasculitis Associated ... • Absence of skin ... min/1.73 m2 at diagnosis ... #Vasculitis #Management ... #Rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Diagnosis Framework ... Urticarial/LCV) - Cryoglobulinemic ... Disease • Cogan syndrome ... #skin #dermatology ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... reticularis & skin ... Labs/Diagnosis: ... Cryoglobulins #diagnosis ... classification #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... /HSP • Cryoglobulinemia ... #hematology #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome ... • Vasculitis ... #differential #diagnosis ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... #rash #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... Vasculitis - Skin ... Low levels mixed cryoglobulinemia ... #rheumatology #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... (Cryoglobulinemic ... Paraproteinemias #Hematology ... #Differential #Diagnosis