13 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
lesions, pyoderma gangrenosum ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Presentation - Systemic Symptoms ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... symptoms by days ... DDX: - Pyoderma gangrenosum ... Leukocytoclastic vasculitis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
UV light Incr cell ... inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... = vasculitis vs ... required due to skip ... #Symptoms #Diagnosis ... #Management
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
contagious of all ... Skin rash and malaise ... The signs and symptoms ... Syphilis #Rash #Diagnosis ... #Clinical #Photo