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treatment rheumatology differential cardiology erythematosus myasthenia syndrome systemic als amyotrophic cardiomyopathy cerebritis classification cns comparison cryoglobulinemia cryoglobulins druginduced encephalopathy endocarditis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... : Chronic disease ... #Management #Summary
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... #CNS #neurology ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... : Chronic disease ... #rheumatology #diagnosis ... #management
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... heavy metals), Critical ... Syndrome, Myasthenia Gravis ... #differential #diagnosis ... #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... disorders (Systemic lupus ... syndrome, Myasthenia gravis ... Manifestations #diagnosis ... #neurology #symptoms
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... myasthenia Diagnosis ... immunosuppressants - Meds ... #diagnosis #management ... #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... - Summary • an ... : • Based on clinical ... #diagnosis #management ... #neurology #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Endocarditis Summary ... • Autoimmune (SLE ... Sanguinis, Mitis, Oralis ... Treat underlying cause ... #management #cardiology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • They can cause ... Syndrome: • Clinical ... • Autoimmune diseases ... (e.g. systemic lupus
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