10 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #Management #Summary ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
- Summary Antinuclear ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... #CNS #neurology ... #rheumatology # ... #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE ... #management #treatment ... #summary #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... myasthenia Diagnosis ... immunosuppressants - Meds ... Myasthenia #Gravis #diagnosis ... #management #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... Clinical Presentation ... GBS), systemic lupus ... erythematosus (SLE ... #management #treatment
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... Differential Diagnosis ... orthopnea, PND, LE ... teratogenic GDMT meds ... #treatment
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... #DIL #rheumatology ... #diagnosis #treatment ... #management