5783 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Phosphatase, ALT ≥ 3x ULN ... Transaminase, ALP ≥ 2x ULN ... Value = (ALT / ULN ... ALT) / (ALP / ULN ... Transaminitis #diagnosis
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
CK: Up to 50X ULN ... CK: Up to 50X ULN ... Associated Features: Diagnosis ... over years, often diagnosed ... #differential #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Severe ALT > 15x ULN ... Moderate ALT 5-15x ULN ... Mild ALT < 5x ULN ... #Differential #Diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Severe - ALT >15X ULN ... Moderate - ALT 5-15X ULN ... Mild - ALT < 5x ULN ... Transaminitis #Algorithm #diagnosis
Rock Paper Scissors - Assessment of Nerve Damage in Upper Limb Injuries
Rock - Median Nerve
 •
(2%), Radius & Ulna ... (5%), Radius & Ulna ... UpperExtremities #diagnosis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
value = (ALT + ULN ... phosphatase + ULN ... Transaminitis #diagnosis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Diagnosis - If suspected ... , AIH diagnosis ... ALT + AST > 10x ULN ... ALT + AST > 5x ULN ... AND IgG > 2x ULN
HAS-BLED Score - Risk of Major Bleeding in 1 Year
Characteristics (1 point each)
 • Hypertension: Baseline
bilirubin > 2x ULN ... /Alk phos > 3x ULN ... anticoagulation #diagnosis
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
distal to distal ulna ... distal radius or ulna ... Radiology #XRay #Diagnosis
Causes of Common Accidental and Non-Accidental Pediatric Fractures - Differential Diagnosis Algorithm
Accidental Trauma
 - Distal Radius
- Differential Diagnosis ... Skull, Spine, Ulna ... #Differential #Diagnosis