213 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... or Cholestatic Liver ... @AnnKumfer #Liver
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... kidney, brain ALT ... specific for the liver ... / ULN ALT) / (ALP ... SinaiBmoreIMRes #Liver
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Severe ALT > 15x ... ULN • Viral ... Differential #Diagnosis #Algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... : • Severe - ALT ... >15X ULN ... Transaminitis #Algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... /ULN ALT) / (Alk ... Identify Acute Liver ... than ALTALT ... : Specific to liver
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... Findings: • ↑AST/ALT ... (5-10x ULN), ↑Tbili ... Cr, ↓Glucose, ↓PLT
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... than ALTALT ... • AST: ↑ • ALT ... - ALP > AST/ALT ... differential #diagnosis #algorithm
Features of Components of Liver Function Tests #Diagnosis #IM #GI #LFTs #Liver #Function #Tests #Locations #AlkPhos
Components of Liver ... #IM #GI #LFTs #Liver ... #AlkPhos #AST #ALT
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... increase in AST/ALT ... compared with AST/ALT ... Diagnosis #hepatology #algorithm
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... Vitals - LFTs, plt ... MELD - Chronic liver ... disease work up - Liver ... US - Prior liver