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diagnosis treatment gastroenterology differential criticalcare peds cardiology ibd hepatology em ddxof hematology pulmonary pediatrics nephrology protocol primarycare emergency evaluation guidelines
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Differential Diagnosis Algorithm ... for Transaminitis ... >15X ULN ... Elevated #Abnormal #Transaminitis ... #Algorithm #diagnosis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
kidney, brain ALT ... R Value = (ALT ... / ULN ALT) / (ALP ... / ULN ALP) ... LFTs #Elevation #Transaminitis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Injury • AST/ALT ... > Alk phos • ALT ... • R value = (ALT ... + ULN ALT) / (alkaline ... #Cholestatic #Transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Differential Diagnosis Algorithm ... Severe ALT > 15x ... ULN • Viral ... HELLP Moderate ALT ... Differential #Diagnosis #Algorithm
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Pattern #LFTs #transaminits ... #differential #algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT ... /ULN ALT) / (Alk ... phos/ULN ALP) ... to liver than ALT ... differential #Hepatology #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
increase in AST/ALT ... compared with AST/ALT ... Diagnosis #hepatology #algorithm ... #Transaminitis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Findings: • ↑AST/ALT ... (5-10x ULN), ↑Tbili ... Cr, ↓Glucose, ↓PLT ... Intrahepatic Cholestasis Management ... obgyn #diagnosis #management
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Hepatitis (eg Viral) Management ... + AST > 10x ULN ... - ALT + AST > ... 5x ULN AND IgG ... AIH #Diagnosis #Management
General Algorithms for Assessment of the Left Ventricular Assist Device (LVAD) (Algorithms 1, 2 and 3) Algorithm
General Algorithms ... Device (LVAD) (Algorithms ... 1, 2 and 3) Algorithm ... LVAD) Patient Algorithm ... #Management #BMJ
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