983 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... value = (ALT + ULN ... phosphatase + ULN ... #differential #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... Value = (ALT / ULN ... SinaiBmoreIMRes #Liver ... Transaminitis #diagnosis #hepatology
Incomplete spinal cord syndromes (ISCS)
 • Central - Small Lesion - Suspended sensory deficit, classic cape
Disproportionate motor (UMN ... Ipsilateral weakness (UMN ... small band of LMN ... paraparesis (mixed UMN ... and LMN types)
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Severe ALT > 15x ULN ... Moderate ALT 5-15x ULN ... Mild ALT < 5x ULN ... Others #LFTs #Hepatology
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... However, in UMN ... UMC & LMN lesions ... UMN lesions are ... @DharSaty #UMN
Bilateral LMN palsy with tongue weakness, wasting and fasciculations.  →  Bulbar motor Neuron disease

Note
Bilateral LMN palsy ... differentiates this from an UMN ... fasciculations #LMN
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
involving both UMN ... combination of UMN ... sclerosis with pure UMN ... involvement • UMN ... combination of UMN
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Severe - ALT >15X ULN ... Moderate - ALT 5-15X ULN ... Mild - ALT < 5x ULN ... Algorithm #diagnosis #hepatology
Focused evaluation algorithm for acute liver injury

#Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
algorithm for acute liver ... injury #Liver ... Algorithm #Diagnosis #Hepatology
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Functions of the Liver ... Pathophysiology #Functions #Liver ... #Hepatology #Synthesis