11 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Cerebral Salt Wasting ... vs SIADH - Pathophysiology ... Neurological event 2) Sodium ... reabsorption 5) ↓ Na ... Pathophysiology #diagnosis #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
- RAAS ON (UNa ... > 30): SIADH, Medications ... Reset osmostat, Cerebral ... Algorithm #diagnosis #sodium ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
or Ineffective (UNa ... , Renal Sodium loss ... Insufficiency, Cerebral ... solute intake, UNa ... #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
acid >4 • Urine Na ... Renal losses, Cerebral ... uric acid <4 • SIADH ... algorithm #diagnosis #sodium ... #low #nephrology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... pain, primary lung ... promoting passive sodium ... SatyaPatelMD #SIADH ... #hyponatremia #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Pain, Primary lung ... promoting passive sodium ... osmolality < 538 AND UNa ... #hyponatremia #nephrology
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
ADH secretion (SIADH ... carcinoma of the lung ... osmostat - Cerebral ... Table #Causes #Sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
consequence of cerebral ... concentration (UNa ... intravascular volume; UNa ... EBV #potomania #SIADH ... #Thiazides #UNAa
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... eye movement • Cerebral ... e.g. narcolepsy, SIADH ... Manifestations #diagnosis #neurology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Water (TBW) x (([Na ... patients at risk for cerebral ... Treatment #management #nephrology ... #sodium