10 results
hyponatremia diagnosis differential algorithm management treatment cancer causes cerebral comparison defects epithelial hypotonic inherited kidney low oncology pathophysiology physiologic saltwasting
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
restriction alone in SIADH ... or Ineffective (UNa ... , Renal Sodium loss ... differential #diagnosis #table ... #sodium #nephrology
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... pain, primary lung ... promoting passive sodium ... SatyaPatelMD #SIADH ... #hyponatremia #nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Salt Wasting vs SIADH ... Neurological event 2) Sodium ... reabsorption 5) ↓ Na ... #SaltWasting #SIADH ... Pathophysiology #diagnosis #nephrology
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
- RAAS ON (UNa ... - RAAS OFF (UNa ... > 30): SIADH, Medications ... Algorithm #diagnosis #sodium ... #nephrology
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Pain, Primary lung ... promoting passive sodium ... osmolality < 538 AND UNa ... #hyponatremia #nephrology
Hyponatremia Differential Diagnosis Table • Step 1: Correct for hyperglycemia. Corrected Na = [(glucose - 100)/
Differential Diagnosis Table ... Corrected Na = [ ... Urine Osm • Na ... Differential #Diagnosis #Table ... #nephrology #sodium
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
acid >4 • Urine Na ... losses • Urine Na ... uric acid <4 • SIADH ... algorithm #diagnosis #sodium ... #low #nephrology
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
ADH secretion (SIADH ... carcinoma of the lung ... Differential #Diagnosis #Table ... #Causes #Sodium
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Renal glucosuria - Na ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Differential #Table
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Vasopressin-dependent - UNa ... following HSCT) - UNa ... inappropriate • SIAD ... tumors, brain or lung ... Cancer #algorithm #nephrology
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