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diagnosis management differential hematology injury nephrology aki neurology oncology treatment algorithm anemia casts classification encephalopathy gravis hepatitis hepatology leukemia liver
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... a.k.a. cardiorenal syndrome ... tubular necrosis (causes ... : sepsis, meds, ... #Kidney #Injury
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... risk-stratification • Risks ... transformation to acute ... Myelodysplastic #Syndrome
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... are seen in acute ... broad - Advanced kidney ... Fatty - Nephrotic syndrome ... ("Maltese cross
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... • Hepatorenal syndrome ... long-term Foley • UTI ... Medications → Stop meds ... #Kidney #Injury
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Anemia of chronic kidney ... disease, Acute ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... Due to synthesis rises ... • Gilbert's syndrome ... cardiac muscle, kidneys
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... muscles: “myasthenic crises ... Myasthenia Crises ... aspiration and acute ... immunosuppressants - Meds
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
• Hypertensive crisis ... Neurological symptoms: Acute ... , ADEM, Acute toxic ... the underlying cause ... until cause identified
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Scleroderma Renal Crisis ... : 1) Acute kidney ... , add other BP meds ... • Refractory cases ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
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