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diagnosis blood product reactions anemia classification coagulation dic differential disseminated ebm hemolytic intravascular prbc thresholds transfusions treatment trials visualabstract
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Blood saves lives ... unnecessary and cause ... Transfusions are ... #Thresholds #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Liver disease ... , spider/snake bites ... prosthetic valve • Transfusion ... classification #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
eruptions, diarrhea, liver ... Citrate in RBCs binds ... RBCs (stored at 4C ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
eruptions, diarrhea, liver ... Citrate in RBCs binds ... RBCs (stored at 4C ... #diagnosis #management ... #hematology #reactions
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... DIC • Severe Liver ... Treat primary cause ... #treatment #management ... #hematology
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