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diagnosis management differential erythematosus lupus oncology sle vasculitis allergy ana anca anemia antibodies antibody antineutrophil antinuclear aplastic behcets cardiology cerebritis
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... Differential #Diagnosis #Causes ... #hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... Anti-UI-ribonucleoprotein ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... drug-induced SLE) • Systemic ... • Sjögren syndrome ... ANCA+ 60% • Eosinophilic ... antibodies #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
and Systemic Symptoms ... Edema in 70% of cases ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... Episodic angioedema+eosinophilia ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
into a 4-pass system ... ESRD & CAD • Eosinophilic ... cell activation syndrome ... Mastocytosis • Other hematologic ... Differential #Diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... - Hepatitis, eosinophilic ... aplastic anemia Treatment ... Anemia #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... tract, and often causes ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis #rheumatology
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