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management differential hematology erythematosus oncology pediatrics sle syndromes systemic activation algorithm bee bleeding cerebritis child cns encephalopathy gravis hemostasis inflammatory
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
and treatment can ... Inflammatory causes ... • Systemic lupus ... #neurology #inflammatory ... #differential #diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Anti-UI-ribonucleoprotein ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
sweats, pallor, bruising ... splenomegaly, abnormal neurology ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
manifestations: from easy bruising ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... SLE (systemic lupus ... #Causes #peds # ... pediatrics #diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
myasthenia Diagnosis ... Myasthenia Crises ... immunosuppressants - Meds ... Myasthenia #Gravis #diagnosis ... #management #neurology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... - Differential Diagnosis ... von Willebrand syndrome ... discern these causes ... #Hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... the underlying cause ... • Treatment of ... until cause identified ... #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
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