9 results
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Environmental factors: UV-light ... (UV-A, UV-B); Viruses
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
Environmental exposure (UV
Kyrle Disease
Acquired perforating dermatitis aka Kyrle disease. #CKD stage 4, scheduled for UV light Rx

- Dr.
scheduled for UV
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
sodium 4% • UV-B
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Discoid Rash • UV
A quick infographic on the importance of sun protection and the various results of sun damage
#sun #damage #UV ... oxidizing agents, and UV ... determinants of UV-susceptibility
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Atopic diseases • UV
Bladder hematoma causing ureteral obstruction
Male presents 1 day after ureteroscopy/stone extraction (5 mm distal uvj stone)
or edema at the UV
Red Eye - Differential Diagnosis Framework

What?
Redness in the eye can be caused by many conditions and
ophthalmicus, UV