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management differential pathophysiology hematology neurology treatment vasculitis arthritis pulmonary classification leukemia lupus manifestations myositis oncology ra rheumatoid sclerosis sle syndromes
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Disease and ILD Complications ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Antiphospholipid Syndrome (Hughes' Syndrome) Antiphospholipid syndrome - an autoimmune condition where the affected individual produces antibodies
(Hughes' Syndrome ... - an autoimmune ... It can cause arterial ... #APLS #Signs #Symptoms ... #Diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... / Symptoms / Complications ... #MSK #pathophysiology ... #diagnosis #symptoms
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS complications ... Myositis, Comorbid autoimmune ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... / Symptoms / Complications ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... and Symptoms: ... Raynaud's, digital ulcers ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... Visual or auditory symptoms ... conjunction with symptoms ... an underlying autoimmune ... consistent with MS
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Airways disease, Complications ... gastritis and peptic ulcer ... Thrombocytosis, Felty's syndrome ... #Symptoms #diagnosis ... #rheumatology
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