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diagnosis rheumatology signs sle table autoantibodies classification complications druginduced erythematosus fever management manifestations mimickers mucocutaneous pericarditis pfapa presentation syndrome systemic
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Nephropathy 16% - Oral ulcers ... (aPL) 30-45% Differential ... autoantibodies #signs #symptoms ... #mimickers #differential
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... > Mouth, Nasal Ulcers ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Constitutional symptoms ... constitutional symptoms ... Alopecia, oral ulcers ... #sle #comparison
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Features That Differentiate ... presentation of systemic lupus ... it difficult to differentiate ... #Pericarditis #Symptoms ... #Presentation #comparison
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 Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... livedo reticularis, ulcers ... genital aphthous ulcers ... such as systemic lupus ... Presentation - Systemic Symptoms
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... Ulcers typically ... frequency than oral ulcers ... reporting such symptoms ... DIFFERENTIAL DIAGNOSIS
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